Non-genetic risk factors for keratoconus

M Song; QY Fang; I Seth; PN Baird; MD Daniell; S Sahebjada

Journal article

Non-genetic risk factors for keratoconus

M Song, QY Fang, I Seth, PN Baird, MD Daniell, S Sahebjada

Clinical and Experimental Optometry | Published : 2023

DOI: 10.1080/08164622.2022.2062222

Abstract

Keratoconus is a complex and multifactorial disease and its exact aetiology remains unknown. This current study examined the important environmental risk factors and their association with keratoconus. This study was registered in the PROSPERO International Prospective Register of systematic reviews under registration number CRD42021256792 in 2021. Scopus, Web of Science, PubMed, and Cochrane CENTRAL databases were searched for all relevant articles published from 1 January 1900 to 31 July 2021. National Institutes of Health Quality Assessment Tool was used to assess the methodological quality of the studies. The assessment for statistical heterogeneity was assessed using the Z-statistics on..

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University of Melbourne Researchers

Paul Baird Author

Mark Daniell Author

Srujana Sahebjada Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This study was supported by the Australian National Health and Medical Research Council (NHMRC) project Ideas grant APP1187763 and Senior Research Fellowship (1138585 to PNB), Lions Eye Donation Service (SS), Angior Family Foundation (SS) and Perpetual Impact Philanthropy grant (SS). The Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government. The sponsor or funding organizations had no role in the design or conduct of this research.